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Thermodynamics of Biomolecular Systems >> Content Detail



Study Materials



Readings

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Reading assignments are from the following textbooks:

[SAB] Amazon logo Silbey, R., R. Alberty, and M. Bawendi. Physical Chemistry. New York, NY: John Wiley & Sons, 2004. ISBN: 9780471215042.

[DB] Amazon logo Dill, Ken A., and Sarina Bromberg. Molecular Driving Forces: Statistical Thermodynamics in Chemistry and Biology. New York, NY: Routledge, 2002. ISBN: 9780815320517.


LEC #TOPICSREADINGS
1Introduction to Thermo; 0th Law; Temperature; Work; HeatSAB 1.1-1.4, 1.8-1.9, 2.1
2State Functions, 1st Law, PathsSAB 2.2-2.6
3Joule and Joule-Thompson; Heat CapacitySAB 2.7-2.9
4Reversible and Irreversible ProcessesSAB 2.10, 3.1
5ThermochemistrySAB 2.11-2.13
62nd Law; Entropy (Boltzmann and Clausius)SAB 3.2
7ΔS for Reversible and Irreversible ProcessesSAB 3.3-3.5
8Equilibrium; Maxwell Relations; Free EnergySAB 4.1-4.2, 4.9

DB 8
9Chemical Potential; Phase EquilibriumSAB 4.3-4.4, 4.6-4.7
10Chemical Equilibrium; Equilibrium ConstantSAB 5.1-5.4
11Standard States; Gibbs-DuhemSAB 4.8
12ΔG0= -RTlnK; ExampleSAB 8.1-8.2
Hour Exam 1
13Boltzmann DistributionDB 6

SAB 3.6, 16.1-16.2
14Thermo and Boltzmann DistributionDB 10 (first half)
15Occupation of StatesDB 10 (second half)
16Third LawSAB 3.8
17Phase Equilibria, Single ComponentSAB 6.1-6.2

DB 14
18Phase Equilibria II; Clausius ClapeyronSAB 6.3
19Regular Solutions; Mixing Energy; Mean FieldsDB 15

Class notes
20Nonideal Solutions
21Solvation; Colligative PropertiesDB 16

Class notes
Hour Exam 2
22Osmotic Pressure and Phase PartitioningDB 16
23Surface TensionDB 14
24Polymer 1 - Freely Jointed ChainDB 31
25Polymer 2 - Chain ConformationDB 31
26Polymer 3 - Rubber ElasticityDB 32
27Electrolyte Solutions
28Electrolytes at Interfaces; Debye LengthClass notes
29Titration of PolyelectrolytesClass notes
30Thermodynamics of DNA HybridizationClass notes
31CooperativityDB 26
Hour Exam 3
32Cooperativity, Part 2DB 28
33Cooperativity, Part 3
34Driving Forces for Self-Assembly
35Special Topic (Coarse Grain/Monte Carlo Model)
36Course Review and Evaluations

 








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