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Course Info

  • Course Number / Code:
  • 7.342 (Fall 2006) 
  • Course Title:
  • Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation 
  • Course Level:
  • Undergraduate 
  • Offered by :
  • Massachusetts Institute of Technology (MIT)
    Massachusetts, United States  
  • Department:
  • Biology 
  • Course Instructor(s):
  • Dr. Matthew Guenther
    Dr. Roshan Kumar 
  • Course Introduction:
  •  


  • 7.342 Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation



    Fall 2006




    Course Highlights


    This literature-based seminar features a complete list of readings.


    Course Description


    In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells? We will explore how stem cell pluripotency is preserved, how master regulators of cell-fate decisions execute developmental programs, and how chromatin regulators control undifferentiated versus differentiated states. Additionally, we will discuss how aberrant regulation of transcriptional regulators produces disorders such as developmental defects and cancer.

    This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

     

ACKNOWLEDGEMENT:
This course content is a redistribution of MIT Open Courses. Access to the course materials is free to all users.






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