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Course Info

  • Course Number / Code:
  • 9.531J (Fall 2004) 
  • Course Title:
  • Systems Biology 
  • Course Level:
  • Graduate 
  • Offered by :
  • Massachusetts Institute of Technology (MIT)
    Massachusetts, United States  
  • Department:
  • Physics 
  • Course Instructor(s):
  • Prof. Alexander van Oudenaarden 
  • Course Introduction:
  •  


  • 8.591J / 7.81J / 9.531J Systems Biology



    Fall 2004




    Course Highlights


    This course features a set of course notes in the readings section.


    Course Description


    This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development.


    Technical Requirements


    MATLAB® software is required to run the .m files found on this course site.

     

ACKNOWLEDGEMENT:
This course content is a redistribution of MIT Open Courses. Access to the course materials is free to all users.






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