Cell-Matrix Mechanics >> Content Detail

Lecture Notes

Lecture Notes

I. Unit Cell Processes and Mechanics of Matrix Molecules and Tissues Structures
1Clinical Examples of the Roles of Mechanical Forces in Tissues and Organs: The Working ParadigmsProf. Spector(PDF)
2Tissue Structures and Unit Cell ProcessesProf. Spector(PDF 1)

(PDF 2)

(PDF 3)
3Cell-Matrix Interactions: Extracellular Matrix Molecules, Adhesion Proteins and IntegrinsProf. Spector(PDF 1)

(PDF 2)
4Models for the Mechanical Behavior of Porous ScaffoldsProf. L. Gibson(PDF)
5Structure-Properties Relationships for TissuesProf. Spector
6Mechanics of Selected TissuesProf. S. Socrate
II. Mechanics of Cells: Effects of Exogenous Forces and Endogenous Force Generation
7Effects of Exogenous Mechanical Forces on CellsProf. Spector
8Response of Cells to Substrate StrainProf. Spector(PDF)
9Endothelial Cell Response to FlowProf. C. F. Dewey
10Quiz 1
11Measuring Cell Contraction

Cell Force Monitor
Brendan Harley(PDF)
12Endogenous Mechanical Force Generation by CellsProf. Spector(PDF 1)

(PDF 2)
13Models for Cell Contraction In Vitro and In VivoProf. Spector(PDF 1)

(PDF 2)
14Mechanical Coupling of Cells with MatrixProf. Yannas(PDF 1)

(PDF 2)
15Cell-matrix Interactions During Wound ClosureProf. Yannas(PDF - 1.6 MB)
16Blockade of Contraction During Induced Organ RegenerationProf. Yannas(PDF - 1.6 MB)
17ReviewProf. Spector
18Quiz 2
III. Tissue Mechanics
19Review of Principles of Linear Elastic MechanicsProf. Yannas(PDF - 1.1 MB)
20Nonlinear Elasticity: Tendon and SkinProf. Yannas(PDF)
21Linear Viscoelastic BehaviorProf. Yannas(PDF - 1.0 MB)
22Response of Articular Cartilage to Mechanical LoadingProf. A. Grodzinsky
23Mechanical Behavior of Ligament, Meniscus and Intervertebral DiscProf. Spector(PDF 1)

(PDF 2)
24Mechanical Behavior of BoneProf. Spector(PDF)
25Response of Bone to Mechanical Loading

Prof. Spector(PDF)
26Quiz 3


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